6OC0
Crystal structure of human DHODH with OSU-03012
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 369 | 40125.9 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (Human) | DHOdehase,Dihydroorotate oxidase |
| 2 | B (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 3 | C (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 4 | D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | G (A) | N-{4-[5-(phenanthren-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}glycinamide | non-polymer | 460.4 | 1 | Chemie (M4J) | |||
| 6 | H (A) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A: 29 - 395 (UniProt: Q02127)
| PDB | External Database | Details |
|---|---|---|
| His 27 | - | expression tag |
| Met 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40125.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1361.1 | |
| All* | Total formula weight | 41487.0 |
