6OBH

Structure of HIV-1 CA 1/2-hexamer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	CA	polymer	232	25618.4	2	UniProt (T2CI25) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (P12493)	Human immunodeficiency virus 1 (HIV-1)
2	B, E (B, E)	CA	polymer	232	25562.4	2	UniProt (B6DRA0) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (P12493)	Human immunodeficiency virus 1 (HIV-1)
3	C, F (C, F)	CA	polymer	232	25618.4	2	UniProt (T2CI25) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (P12493)	Human immunodeficiency virus 1 (HIV-1)
4	G, H, I, J, K... (A, B, D, E, F)	SODIUM ION	non-polymer		23.0	6	Chemie (NA)
5	M, N, O (A, C, E)	water	water		18.0	3	Chemie (HOH)

Sequence modifications

A, D: 1 - 231 (UniProt: T2CI25)

PDB	External Database	Details
Met 0	-	initiating methionine
Cys 14	Ala 120	engineered mutation
Ala 184	Trp 290	engineered mutation
Ala 185	Met 291	engineered mutation

B, E: 1 - 231 (UniProt: B6DRA0)

PDB	External Database	Details
Met 0	-	initiating methionine
Cys 45	Glu 177	engineered mutation
Cys 54	Thr 186	engineered mutation
Ala 184	Trp 316	engineered mutation
Ala 185	Met 317	engineered mutation

C, F: 1 - 231 (UniProt: T2CI25)

PDB	External Database	Details
Met 0	-	initiating methionine
Cys 42	Ala 148	engineered mutation
Ala 184	Trp 290	engineered mutation
Ala 185	Met 291	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	153598.6
Non-Polymers*	Number of molecules	6
	Total formula weight	137.9
All*	Total formula weight	153736.6

*Water molecules are not included.