6OB6
Human equilibrative nucleoside transporter-1, S-(4-nitrobenzyl)-6-thioinosine bound, merohedrally twinned
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Equilibrative nucleoside transporter 1 | polymer | 442 | 48863.7 | 2 | UniProt (Q99808) Pfam (PF01733) | Homo sapiens (Human) | Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter,Equilibrative NBMPR-sensitive nucleoside transporter,Nucleoside transporter,es-type,Solute carrier family 29 member 1 |
| 2 | C, D (A, B) | 6-{[(4-nitrophenyl)methyl]sulfanyl}-9-beta-D-ribofuranosyl-9H-purine | non-polymer | 419.4 | 2 | Chemie (NBM) PubChem (5129) PubChem (65407) PubChem (6568857) PubChem (9931917) PubChem (11957642) PubChem (16395538) PubChem (24867516) PubChem (25886576) PubChem (38988593) PubChem (38988684) PubChem (40920331) PubChem (46875433) PubChem (1753968) PubChem (40468121) PubChem (57244712) PubChem (14519594) PubChem (118705490) PubChem (124404356) |
Sequence modifications
A, B: 2 - 456 (UniProt: Q99808)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Phe 168 | Leu 168 | engineered mutation |
| Ala 175 | Pro 175 | engineered mutation |
| - | Pro 243 | deletion |
| - | Gly 244 | deletion |
| - | Glu 245 | deletion |
| - | Gln 246 | deletion |
| - | Glu 247 | deletion |
| - | Thr 248 | deletion |
| - | Lys 249 | deletion |
| - | Leu 250 | deletion |
| - | Asp 251 | deletion |
| - | Leu 252 | deletion |
| - | Ile 253 | deletion |
| - | Ser 254 | deletion |
| - | Lys 255 | deletion |
| - | Gly 256 | deletion |
| - | Glu 257 | deletion |
| - | Glu 258 | deletion |
| - | Pro 259 | deletion |
| - | Arg 260 | deletion |
| - | Ala 261 | deletion |
| - | Gly 262 | deletion |
| - | Lys 263 | deletion |
| - | Glu 264 | deletion |
| - | Glu 265 | deletion |
| - | Ser 266 | deletion |
| - | Gly 267 | deletion |
| - | Val 268 | deletion |
| - | Ser 269 | deletion |
| - | Val 270 | deletion |
| - | Ser 271 | deletion |
| - | Asn 272 | deletion |
| - | Ser 273 | deletion |
| - | Gln 274 | deletion |
| Lys 288 | Asn 288 | engineered mutation |
| Gly 457 | - | expression tag |
| Thr 458 | - | expression tag |
| Glu 459 | - | expression tag |
| Leu 460 | - | expression tag |
| Leu 461 | - | expression tag |
| Gln 462 | - | expression tag |
| Val 463 | - | expression tag |
| Asp 464 | - | expression tag |
| Thr 465 | - | expression tag |
| Asn 466 | - | expression tag |
| Ser 467 | - | expression tag |
| Leu 468 | - | expression tag |
| Glu 469 | - | expression tag |
| Val 470 | - | expression tag |
| Leu 471 | - | expression tag |
| Phe 472 | - | expression tag |
| Gln 473 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97727.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 838.8 | |
| All* | Total formula weight | 98566.2 |
