6OB6
Human equilibrative nucleoside transporter-1, S-(4-nitrobenzyl)-6-thioinosine bound, merohedrally twinned
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Equilibrative nucleoside transporter 1 | polymer | 442 | 48863.7 | 2 | UniProt (Q99808) Pfam (PF01733) | Homo sapiens (Human) | Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter,Equilibrative NBMPR-sensitive nucleoside transporter,Nucleoside transporter,es-type,Solute carrier family 29 member 1 |
| 2 | C, D (A, B) | 6-{[(4-nitrophenyl)methyl]sulfanyl}-9-beta-D-ribofuranosyl-9H-purine | non-polymer | 419.4 | 2 | Chemie (NBM) |
Sequence modifications
A, B: 2 - 456 (UniProt: Q99808)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Phe 168 | Leu 168 | engineered mutation |
| Ala 175 | Pro 175 | engineered mutation |
| - | Pro 243 | deletion |
| - | Gly 244 | deletion |
| - | Glu 245 | deletion |
| - | Gln 246 | deletion |
| - | Glu 247 | deletion |
| - | Thr 248 | deletion |
| - | Lys 249 | deletion |
| - | Leu 250 | deletion |
| - | Asp 251 | deletion |
| - | Leu 252 | deletion |
| - | Ile 253 | deletion |
| - | Ser 254 | deletion |
| - | Lys 255 | deletion |
| - | Gly 256 | deletion |
| - | Glu 257 | deletion |
| - | Glu 258 | deletion |
| - | Pro 259 | deletion |
| - | Arg 260 | deletion |
| - | Ala 261 | deletion |
| - | Gly 262 | deletion |
| - | Lys 263 | deletion |
| - | Glu 264 | deletion |
| - | Glu 265 | deletion |
| - | Ser 266 | deletion |
| - | Gly 267 | deletion |
| - | Val 268 | deletion |
| - | Ser 269 | deletion |
| - | Val 270 | deletion |
| - | Ser 271 | deletion |
| - | Asn 272 | deletion |
| - | Ser 273 | deletion |
| - | Gln 274 | deletion |
| Lys 288 | Asn 288 | engineered mutation |
| Gly 457 | - | expression tag |
| Thr 458 | - | expression tag |
| Glu 459 | - | expression tag |
| Leu 460 | - | expression tag |
| Leu 461 | - | expression tag |
| Gln 462 | - | expression tag |
| Val 463 | - | expression tag |
| Asp 464 | - | expression tag |
| Thr 465 | - | expression tag |
| Asn 466 | - | expression tag |
| Ser 467 | - | expression tag |
| Leu 468 | - | expression tag |
| Glu 469 | - | expression tag |
| Val 470 | - | expression tag |
| Leu 471 | - | expression tag |
| Phe 472 | - | expression tag |
| Gln 473 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97727.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 838.8 | |
| All* | Total formula weight | 98566.2 |
