6OAR

Structure of the Kupe virus OTU bound to the C-terminal domain of sheep ISG15

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, C, E, G)	RNA-dependent RNA polymerase	polymer	178	20392.9	4	UniProt (B8PWH5) Pfam (PF02338)	Kupe virus
2	B, D, F, H (B, D, F, H)	Interferon stimulated gene 17	polymer	78	8916.1	4	UniProt (Q9GKP4)	Ovis aries (Sheep)
3	I, J, K, L (A, C, E, G)	prop-2-en-1-amine	non-polymer		57.1	4	Chemie (AYE)
4	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	359	Chemie (HOH)

Sequence modifications

A, C, E, G: 1 - 169 (UniProt: B8PWH5)

PDB	External Database	Details
Ser 170	-	expression tag
Gly 171	-	expression tag
Ser 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag

B, D, F, H: 80 - 156 (UniProt: Q9GKP4)

PDB	External Database	Details
Met 79	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	117236.1
Non-Polymers*	Number of molecules	4
	Total formula weight	228.4
All*	Total formula weight	117464.5

*Water molecules are not included.