6O9B

Crystal structure of HLA-A3*01 in complex with a wild-type beta-catenin peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HLA class I histocompatibility antigen, A-3 alpha chain	polymer	300	34589.2	1	UniProt (P04439) Pfam (PF00129) Pfam (PF07654) In PDB	Homo sapiens (Human)	MHC class I antigen A*3
2	B	Beta-2-microglobulin	polymer	119	13732.5	1	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	C	Catenin beta-1	polymer	9	862.0	1	UniProt (P35222) In PDB	Homo sapiens	Beta-catenin
4	A, B	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
5	A, B	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	3	Chemie (MES)
6	A	IMIDAZOLE	non-polymer		69.1	2	Chemie (IMD)
7	A, B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
8	A, B	1,2-ETHANEDIOL	non-polymer		62.1	7	Chemie (EDO)
9		water	water		18.0	166	Chemie (HOH)

Sequence modifications

A: 1 - 280 (UniProt: P04439)

PDB	External Database	Details
Met -2	-	cloning artifact
Ala -1	-	cloning artifact
Ser 0	-	cloning artifact
Gly 281	-	expression tag
Ser 282	-	expression tag
Leu 283	-	expression tag
His 284	-	expression tag
His 285	-	expression tag
Ile 286	-	expression tag
Leu 287	-	expression tag
Asp 288	-	expression tag
Ala 289	-	expression tag
Gln 290	-	expression tag
Lys 291	-	expression tag
Met 292	-	expression tag
Val 293	-	expression tag
Trp 294	-	expression tag
Asn 295	-	expression tag
His 296	-	expression tag
Arg 297	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	49183.7
Non-Polymers*	Number of molecules	18
	Total formula weight	1971.3
All*	Total formula weight	51155.0

*Water molecules are not included.