6O8D

Anti-CD28xCD3 CODV Fab bound to CD28

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C	T-cell-specific surface glycoprotein CD28	polymer	126	14617.5	1	UniProt (P10747) Pfam (PF15910) In PDB	Homo sapiens (Human)	TP44
2	L	Anti-CD28xCD3 CODV Fab Light chain	polymer	338	36794.9	1		Homo sapiens (human)
3	H	Anti-CD28xCD3 CODV Fab Heavy chain	polymer	358	39192.7	1		Homo sapiens (human)
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

C: 19 - 136 (UniProt: P10747)

PDB	External Database	Details
His 137	-	expression tag
His 138	-	expression tag
His 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	90605.2
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	91250.8

*Water molecules are not included.