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6O72

Structure of the TRPM8 cold receptor by single particle electron cryo-microscopy, TC-I 2014-bound state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transient receptor potential cation channel subfamily M member 8polymer1098126989.84Parus major (Great Tit)
2E, M, S, Z
(A, B, C, D)
CHOLESTEROL HEMISUCCINATEnon-polymer486.74Chemie (Y01)
3AA, CA, F, H, L...
(D, A, B, C)
UNDECANEnon-polymer156.38Chemie (UND)
4BA, G, O, U
(D, A, B, C)
(1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoatenon-polymer593.84Chemie (9PE)
5DA, I, P, W
(D, A, B, C)
3-{7-(trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl}-1-oxa-2-azaspiro[4.5]dec-2-enenon-polymer467.44Chemie (T14)
6EA, FA, J, K, Q...
(D, A, B, C)
SODIUM IONnon-polymer23.08Chemie (NA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight507959.2
Non-Polymers*Number of molecules28
Total formula weight7626.0
All*Total formula weight515585.2
*Water molecules are not included.

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PDB entries from 2024-11-13

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