6O4U

Co-crystal structure of Mcl1 with inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Induced myeloid leukemia cell differentiation protein Mcl-1	polymer	156	17793.2	2	UniProt (Q07820) Pfam (PF00452) In PDB	Homo sapiens (Human)	Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT
2	A, B	(2~{S})-4-(cyclobutylmethyl)-2-(2,4-dichlorophenyl)-~{N}-(2-methylpropylsulfonyl)-2,3-dihydro-1,4-benzoxazine-6-carboxamide	non-polymer		511.5	2	Chemie (LMV)
3		water	water		18.0	256	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35586.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1022.9
All*	Total formula weight	36609.4

*Water molecules are not included.