6O4U
Co-crystal structure of Mcl1 with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 156 | 17793.2 | 2 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | C, D (A, B) | (2~{S})-4-(cyclobutylmethyl)-2-(2,4-dichlorophenyl)-~{N}-(2-methylpropylsulfonyl)-2,3-dihydro-1,4-benzoxazine-6-carboxamide | non-polymer | 511.5 | 2 | Chemie (LMV) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35586.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1022.9 | |
| All* | Total formula weight | 36609.4 |
