6O4P

The crystal structure of the interleukin 11 alpha receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Interleukin-11 receptor subunit alpha	polymer	349	38211.7	2	UniProt (Q14626)	Homo sapiens (Human)	IL-11RA
2	C (C)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
3	D (D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	F, G, H, I, J... (A, B)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)

Sequence modifications

A, B: 1 - 341 (UniProt: Q14626)

PDB	External Database	Details
Ser 226	Cys 248	conflict
His 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag
His 349	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76423.3
Branched	Number of molecules	2
	Total formula weight	1173.1
Non-Polymers*	Number of molecules	12
	Total formula weight	1277.9
All*	Total formula weight	78874.3

*Water molecules are not included.