6O3P
Crystal structure of the catalytic domain of mouse Nudt12 in complex with AMP and 3 Mg2+ ions
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisomal NADH pyrophosphatase NUDT12 | polymer | 339 | 37739.3 | 2 | UniProt (Q9DCN1) Pfam (PF09296) Pfam (PF09297) Pfam (PF00293) | Mus musculus (Mouse) | Nucleoside diphosphate-linked moiety X motif 12,Nudix motif 12 |
| 2 | C, I (A, B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 3 | D, E, F, J, K... (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 4 | G, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 290 | Chemie (HOH) |
Sequence modifications
A, B: 126 - 460 (UniProt: Q9DCN1)
| PDB | External Database | Details |
|---|---|---|
| Gly 122 | - | expression tag |
| Ser 123 | - | expression tag |
| His 124 | - | expression tag |
| Met 125 | - | expression tag |
| Ala 219 | Glu 219 | engineered mutation |
| Ala 220 | Glu 220 | engineered mutation |
| Ala 221 | Glu 221 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75478.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 971.1 | |
| All* | Total formula weight | 76449.6 |
