6O3O
Structure of human DNAM-1 (CD226) bound to nectin-like protein-5 (necl-5)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CD226 antigen | polymer | 243 | 27690.2 | 2 | UniProt (Q15762) Pfam (PF07686) | Homo sapiens (Human) | DNAX accessory molecule 1,DNAM-1 |
| 2 | C, D (C, D) | Poliovirus receptor | polymer | 317 | 34697.1 | 2 | UniProt (P15151) Pfam (PF07686) Pfam (PF08205) | Homo sapiens (Human) | Nectin-like protein 5,NECL-5 |
| 3 | E, G (E, G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 2 | In PDB GlyTouCan (G32152BH) | |||
| 4 | F (F) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G42466VF) | |||
| 5 | H (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | I, J, K, L, O... (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 7 | M, N, W (A, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 8 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A, B: 19 - 250 (UniProt: Q15762)
C, D: 28 - 334 (UniProt: P15151)
| PDB | External Database | Details |
|---|---|---|
| Thr 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Gly 251 | - | expression tag |
| Thr 252 | - | expression tag |
| Lys 253 | - | expression tag |
| His 254 | - | expression tag |
| His 255 | - | expression tag |
| His 256 | - | expression tag |
| His 257 | - | expression tag |
| His 258 | - | expression tag |
| His 259 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 26 | - | expression tag |
| Glu 27 | - | expression tag |
| Thr 335 | - | expression tag |
| Ser 336 | - | expression tag |
| His 337 | - | expression tag |
| His 338 | - | expression tag |
| His 339 | - | expression tag |
| His 340 | - | expression tag |
| His 341 | - | expression tag |
| His 342 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 124774.4 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2784.6 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2942.7 | |
| All* | Total formula weight | 130501.7 |
