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6O3G

Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41).

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(L, B, D, F)
PGZL1 light chainpolymer21523300.74Homo sapiens
2B, D, F, H
(H, A, C, E)
PGZL1 heavy chainpolymer22723913.94Homo sapiens
3I, J, K, L
(Q, S, G, I)
MEPER peptide, region 671-683 of HIV-1 gp41polymer162187.64UniProt (by SIFTS) (P04578)Human immunodeficiency virus 1PEPTIDE EPITOPE OF PGZL1
4M
(L)
GLYCEROLnon-polymer92.11Chemie (GOL)
5N, O, P, Q
(H, A, C, E)
SULFATE IONnon-polymer96.14Chemie (SO4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight197609.0
Non-Polymers*Number of molecules5
Total formula weight476.3
All*Total formula weight198085.3
*Water molecules are not included.

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PDB entries from 2024-10-30

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