6O22

Structure of Asf1-H3:H4-Rtt109-Vps75 histone chaperone-lysine acetyltransferase complex with the histone substrate.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Vacuolar protein sorting-associated protein 75	polymer	264	30656.1	2	UniProt (P53853) Pfam (PF00956) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
2	C	Histone acetyltransferase RTT109	polymer	442	50765.4	1	UniProt (Q07794) Pfam (PF08214) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Regulator of Ty1 transposition protein 109
3	D	Histone chaperone ASF1	polymer	279	31585.1	1	UniProt (P32447) Pfam (PF04729) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Anti-silencing function protein 1,yASF1
4	E	Histone H3.2	polymer	136	15421.1	1	UniProt (P84233) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)	Histone H3
5	F	Histone H4	polymer	103	11394.4	1	UniProt (P62799) Pfam (PF15511) In PDB	Xenopus laevis (African clawed frog)

Sequence modifications

C: 1 - 436 (UniProt: Q07794)

PDB	External Database	Details
Gly -5	-	expression tag
Met -4	-	expression tag
Asp -3	-	expression tag
Pro -2	-	expression tag
Asn -1	-	expression tag
Ser 0	-	expression tag

D: 2 - 279 (UniProt: P32447)

PDB	External Database	Details
Ser 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	170478.3
All*	Total formula weight	170478.3

*Water molecules are not included.