6O04
M.tb MenD IntII bound with Inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D, B, C | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | polymer | 574 | 60068.9 | 4 | UniProt (P9WK11) Pfam (PF02776) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | SEPHCHC synthase,Menaquinone biosynthesis protein MenD |
2 | A, D, B, C | 1,4-dihydroxy-2-naphthoic acid | non-polymer | 204.2 | 4 | Chemie (DNA) | |||
3 | A, B | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
4 | A | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
5 | D, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | D, C | (1~{R},2~{S},5~{S},6~{S})-2-[(1~{S})-1-[3-[(4-azanylidene-2-methyl-1~{H}-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl (phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-1,4-bis(oxidanyl)-4-oxidanylidene-butyl]-6-oxidanyl-5-(3-oxid anyl-3-oxidanylidene-prop-1-en-2-yl)oxy-cyclohex-3-ene-1-carboxylic acid | non-polymer | 753.6 | 2 | Chemie (TOI) | |||
7 | B | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
8 | water | water | 18.0 | 419 | Chemie (HOH) |
Sequence modifications
A, D, B, C: 1 - 554 (UniProt: P9WK11)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 240275.8 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 2618.1 | |
All* | Total formula weight | 242893.9 |