6NZ7

Crystal structure of broadly neutralizing Influenza A antibody 429 B01 in complex with Hemagglutinin Hong Kong 1968

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Hemagglutinin HA1 chain	polymer	319	35154.5	2	UniProt (Q91MA7) Pfam (PF00509) In PDB	Influenza A virus (strain A/Hong Kong/1/1968 H3N2)
2	B, F	Hemagglutinin HA2 chain	polymer	173	19980.1	2	UniProt (Q91MA7) Pfam (PF00509) In PDB	Influenza A virus (strain A/Hong Kong/1/1968 H3N2)
3	H, G	429 B01 FAB heavy chain	polymer	228	24123.1	2	UniProt (A8K008) Pfam (PF07686) Pfam (PF07654) In PDB	Homo sapiens (Human)
4	L, I	429 B01 FAB light chain	polymer	214	23351.0	2	UniProt (Q8TCD0) Pfam (PF07686) Pfam (PF07654) In PDB	Homo sapiens (Human)
5	A, B, H, E, F...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	11	Chemie (NAG)
6		water	water		18.0	19	Chemie (HOH)

Sequence modifications

A, E: 8 - 326 (UniProt: Q91MA7)

PDB	External Database	Details
Glu 218	Gly 234	conflict

H, G: 1 - 114 (PDB: 6NZ7)
H, G: 115 - 228 (UniProt: A8K008)
L, I: 1 - 104 (PDB: 6NZ7)
L, I: 105 - 214 (UniProt: Q8TCD0)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	205217.3
Non-Polymers*	Number of molecules	11
	Total formula weight	2433.3
All*	Total formula weight	207650.5

*Water molecules are not included.