6NWK
Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with dexamethasone and PGC1a coregulator fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | glucocorticoid receptor | polymer | 249 | 28778.5 | 1 | Homo sapiens | ||
| 2 | B | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | polymer | 12 | 1265.6 | 1 | UniProt (Q9UBK2) In PDB | Homo sapiens | PPARGC-1-alpha,Ligand effect modulator 6 |
| 3 | A | DEXAMETHASONE | non-polymer | 392.5 | 1 | Chemie (DEX) | |||
| 4 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 5 | A | ACETYL GROUP | non-polymer | 44.1 | 1 | Chemie (ACE) | |||
| 6 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 7 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30044.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 730.9 | |
| All* | Total formula weight | 30775.1 |
