6NS0

Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis complexed with L-lysine and Cladosporin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Lysine--tRNA ligase	polymer	534	61183.1	2	UniProt (B0BAN6) Pfam (PF01336) Pfam (PF00152)	Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)	Lysyl-tRNA synthetase,LysRS
2	C, CA (A, B)	LYSINE	non-polymer		147.2	2	Chemie (LYS)
3	D, DA (A, B)	cladosporin	non-polymer		292.3	2	Chemie (KRS)
4	E, FA (A, B)	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
5	AA, BA, EA, F, G... (B, A)	1,2-ETHANEDIOL	non-polymer		62.1	34	Chemie (EDO)
6	X (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
7	Y, Z (A)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
8	TA (B)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
9	UA, VA (A, B)	water	water		18.0	463	Chemie (HOH)

Sequence modifications

A, B: 1 - 526 (UniProt: B0BAN6)

PDB	External Database	Details
Met -7	-	expression tag
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	122366.2
Non-Polymers*	Number of molecules	44
	Total formula weight	3565.4
All*	Total formula weight	125931.5

*Water molecules are not included.