Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004824 | molecular_function | lysine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004824 | molecular_function | lysine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| B | 0016874 | molecular_function | ligase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue LYS A 601 |
| Chain | Residue |
| A | GLY225 |
| A | GLY491 |
| A | GLY493 |
| A | KRS602 |
| A | HOH750 |
| A | SER247 |
| A | GLU249 |
| A | ARG271 |
| A | GLU287 |
| A | TYR289 |
| A | ASN441 |
| A | TYR443 |
| A | GLU445 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue KRS A 602 |
| Chain | Residue |
| A | ARG271 |
| A | GLU273 |
| A | THR278 |
| A | HIS279 |
| A | ASN280 |
| A | PHE283 |
| A | MET285 |
| A | LEU439 |
| A | CYS440 |
| A | ASN441 |
| A | GLY493 |
| A | ILE494 |
| A | GLY495 |
| A | ARG498 |
| A | ILE509 |
| A | LYS601 |
| A | HOH802 |
| A | HOH862 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue PG4 A 603 |
| Chain | Residue |
| A | GLY224 |
| A | GLY225 |
| A | ALA226 |
| A | GLU227 |
| A | THR412 |
| A | THR413 |
| A | PRO414 |
| A | TYR443 |
| A | ASP475 |
| A | HOH713 |
| A | HOH796 |
| A | HOH841 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | ASN29 |
| A | PRO32 |
| A | LEU153 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 605 |
| Chain | Residue |
| A | PHE76 |
| A | ILE120 |
| A | GLU121 |
| A | LEU124 |
| A | ASP125 |
| A | LEU126 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | ARG77 |
| A | PHE84 |
| A | GLN95 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 607 |
| Chain | Residue |
| A | PRO162 |
| A | ILE183 |
| A | SER184 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 608 |
| Chain | Residue |
| A | VAL188 |
| A | THR191 |
| A | THR504 |
| A | ALA506 |
| A | ASP511 |
| A | HOH775 |
| A | HOH869 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 609 |
| Chain | Residue |
| A | GLU213 |
| A | GLU215 |
| B | ARG203 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 610 |
| Chain | Residue |
| A | LEU199 |
| A | ARG203 |
| B | ARG203 |
| B | GLU213 |
| B | GLU215 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 611 |
| Chain | Residue |
| A | LEU219 |
| A | GLN220 |
| A | THR221 |
| A | EDO612 |
| B | PHE515 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 612 |
| Chain | Residue |
| A | GLN220 |
| A | ALA251 |
| A | LYS254 |
| A | EDO611 |
| A | HOH702 |
| B | PHE515 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 613 |
| Chain | Residue |
| A | TYR350 |
| A | LYS398 |
| A | ILE400 |
| A | ALA401 |
| A | HIS403 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 614 |
| Chain | Residue |
| A | LYS344 |
| A | THR425 |
| A | LEU426 |
| A | HOH797 |
| A | HOH803 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 615 |
| Chain | Residue |
| A | HOH853 |
| A | MET343 |
| A | ALA388 |
| A | ASP392 |
| A | GLU431 |
| A | HOH705 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 616 |
| Chain | Residue |
| A | LYS344 |
| A | ASP354 |
| A | VAL355 |
| A | ASP356 |
| A | HOH790 |
| A | HOH944 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 617 |
| Chain | Residue |
| A | LEU450 |
| A | ARG453 |
| A | LEU479 |
| A | CYS483 |
| B | TYR7 |
| B | LEU8 |
| B | TYR13 |
| B | HOH863 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 618 |
| Chain | Residue |
| A | ARG197 |
| A | LEU201 |
| site_id | AE1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 619 |
| Chain | Residue |
| A | GLU273 |
| A | GLY274 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 620 |
| Chain | Residue |
| A | MET299 |
| A | GLU303 |
| A | PRO337 |
| A | TRP338 |
| A | ARG340 |
| A | HIS404 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 621 |
| Chain | Residue |
| A | ASP207 |
| A | PHE211 |
| A | LEU212 |
| A | GLU213 |
| B | SER196 |
| B | LYS200 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 622 |
| Chain | Residue |
| A | ARG420 |
| B | PRO32 |
| B | TYR33 |
| B | GLN34 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 623 |
| Chain | Residue |
| A | LYS463 |
| A | ASN466 |
| A | SER469 |
| A | HOH885 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 624 |
| Chain | Residue |
| A | GLU368 |
| A | HOH728 |
| A | HOH926 |
| A | HOH948 |
| site_id | AE7 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 701 |
| Chain | Residue |
| A | TYR7 |
| A | LEU8 |
| A | TYR13 |
| B | PRO449 |
| B | LEU450 |
| B | ARG453 |
| B | LEU479 |
| B | CYS483 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 702 |
| Chain | Residue |
| A | SER261 |
| A | HOH771 |
| B | GLU40 |
| B | ASP89 |
| B | HOH913 |
| site_id | AE9 |
| Number of Residues | 13 |
| Details | binding site for residue LYS B 703 |
| Chain | Residue |
| B | GLY225 |
| B | ALA226 |
| B | SER247 |
| B | GLU249 |
| B | ARG271 |
| B | GLU287 |
| B | TYR289 |
| B | ASN441 |
| B | TYR443 |
| B | GLU445 |
| B | GLY491 |
| B | KRS704 |
| B | HOH844 |
| site_id | AF1 |
| Number of Residues | 16 |
| Details | binding site for residue KRS B 704 |
| Chain | Residue |
| B | ARG271 |
| B | GLU273 |
| B | THR278 |
| B | HIS279 |
| B | ASN280 |
| B | PHE283 |
| B | LEU439 |
| B | CYS440 |
| B | ASN441 |
| B | GLY493 |
| B | ILE494 |
| B | GLY495 |
| B | ARG498 |
| B | LYS703 |
| B | HOH867 |
| B | HOH930 |
| site_id | AF2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 705 |
| Chain | Residue |
| B | LEU73 |
| B | PHE76 |
| B | ILE120 |
| B | GLU121 |
| B | LEU124 |
| B | ASP125 |
| B | HOH801 |
| site_id | AF3 |
| Number of Residues | 11 |
| Details | binding site for residue PG4 B 706 |
| Chain | Residue |
| B | GLY224 |
| B | GLY225 |
| B | ALA226 |
| B | THR412 |
| B | THR413 |
| B | PRO414 |
| B | ASN441 |
| B | TYR443 |
| B | GLN459 |
| B | ASP475 |
| B | HOH817 |
| site_id | AF4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 707 |
| Chain | Residue |
| B | ALA388 |
| B | ASP392 |
| B | GLU431 |
| site_id | AF5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 708 |
| site_id | AF6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 709 |
| Chain | Residue |
| B | ASN29 |
| B | HOH847 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 710 |
| Chain | Residue |
| A | LEU450 |
| B | TYR13 |
| B | HOH863 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 711 |
| Chain | Residue |
| B | GLU22 |
| B | LEU26 |
| B | LYS123 |
| B | HOH827 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 712 |
| Chain | Residue |
| B | ARG45 |
| B | GLN86 |
| B | GLN95 |
| B | GLU143 |
| B | HOH815 |
| site_id | AG1 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 713 |
| site_id | AG2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 714 |
| Chain | Residue |
| A | HOH780 |
| B | PRO162 |
| B | ASP170 |
| B | ARG174 |
| B | HOH909 |
| site_id | AG3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 715 |
| Chain | Residue |
| A | PHE515 |
| B | ALA251 |
| B | LYS254 |
| B | EDO716 |
| site_id | AG4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 716 |
| Chain | Residue |
| A | PHE515 |
| A | PRO516 |
| B | LEU219 |
| B | GLN220 |
| B | EDO715 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 717 |
| Chain | Residue |
| B | ASP276 |
| B | ARG277 |
| B | THR278 |
| B | HOH897 |
| site_id | AG6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 718 |
| Chain | Residue |
| B | LYS344 |
| B | ARG383 |
| B | ILE387 |
| B | THR425 |
| site_id | AG7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 719 |
| Chain | Residue |
| B | GLU273 |
| B | GLY274 |
| B | ASP276 |
| B | HIS279 |
| site_id | AG8 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 720 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00252","evidenceCode":"ECO:0000255"}]} |
