6NR0
SIRT2(56-356) with covalent intermediate between mechanism-based inhibitor Glucose-TM-1beta and 1'-SH ADP-ribose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NAD-dependent protein deacetylase sirtuin-2 | polymer | 319 | 36159.7 | 2 | UniProt (Q8IXJ6) Pfam (PF02146) | Homo sapiens (Human) | Regulatory protein SIR2 homolog 2,SIR2-like protein 2 |
| 2 | C, J (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, K (A, B) | N~2~-[3-(2-hydroxyethoxy)propanoyl]-N-phenyl-N~6~-tetradecanethioyl-L-lysinamide | non-polymer | 563.8 | 2 | Chemie (KXJ) | |||
| 4 | E, L (A, B) | [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-sulfanyl-oxolan-2-yl]methyl hydrogen phosphate | non-polymer | 575.4 | 2 | Chemie (KXG) | |||
| 5 | F, G, M, N (A, B) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 6 | H, O (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | I, P, Q, R (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 8 | S, T (A, B) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72319.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3061.7 | |
| All* | Total formula weight | 75381.1 |
