Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
| A | 0051287 | molecular_function | NAD binding |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
| B | 0051287 | molecular_function | NAD binding |
| B | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | CYS195 |
| A | CYS200 |
| A | CYS221 |
| A | CYS224 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 404 |
| Chain | Residue |
| A | GLU288 |
| A | KXG403 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 405 |
| Chain | Residue |
| A | GLY306 |
| A | ASP308 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | LEU162 |
| A | LYS253 |
| A | ARG78 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 407 |
| Chain | Residue |
| A | TRP320 |
| A | LEU321 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 401 |
| Chain | Residue |
| B | CYS195 |
| B | CYS200 |
| B | CYS221 |
| B | CYS224 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 404 |
| Chain | Residue |
| B | ALA85 |
| B | PHE96 |
| B | GLN167 |
| B | ASN168 |
| B | KXG403 |
| B | HOH554 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue NA B 405 |
| Chain | Residue |
| B | GLU288 |
| B | KXG403 |
| B | HOH501 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 406 |
| Chain | Residue |
| A | GLN292 |
| A | HOH531 |
| B | ARG97 |
| B | TYR104 |
| B | GLU116 |
| B | GLN265 |
| B | HOH524 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 407 |
| Chain | Residue |
| B | TRP320 |
| B | LEU321 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 409 |
| Chain | Residue |
| B | GLU333 |
| B | GLY336 |
| B | LYS338 |
| B | LYS339 |
| site_id | AD3 |
| Number of Residues | 32 |
| Details | binding site for residues KXJ A 402 and KXG A 403 |
| Chain | Residue |
| A | GLY84 |
| A | ALA85 |
| A | GLY86 |
| A | THR89 |
| A | ASP95 |
| A | PHE96 |
| A | ARG97 |
| A | PHE119 |
| A | LEU138 |
| A | PRO140 |
| A | GLN167 |
| A | HIS187 |
| A | ILE232 |
| A | VAL233 |
| A | PHE235 |
| A | GLY236 |
| A | GLU237 |
| A | SER238 |
| A | LEU239 |
| A | GLY261 |
| A | THR262 |
| A | SER263 |
| A | GLN267 |
| A | PRO268 |
| A | ASN286 |
| A | LYS287 |
| A | GLU288 |
| A | GLY322 |
| A | GLU323 |
| A | CYS324 |
| A | NA404 |
| A | HOH536 |
| site_id | AD4 |
| Number of Residues | 33 |
| Details | binding site for residues KXJ B 402 and KXG B 403 |
| Chain | Residue |
| B | GLY322 |
| B | GLU323 |
| B | CYS324 |
| B | NA404 |
| B | NA405 |
| B | GLY84 |
| B | ALA85 |
| B | GLY86 |
| B | THR89 |
| B | ASP95 |
| B | PHE96 |
| B | ARG97 |
| B | SER98 |
| B | PHE119 |
| B | PHE131 |
| B | LEU134 |
| B | LEU138 |
| B | GLN167 |
| B | HIS187 |
| B | ILE232 |
| B | VAL233 |
| B | PHE235 |
| B | GLY236 |
| B | GLU237 |
| B | GLY261 |
| B | THR262 |
| B | SER263 |
| B | VAL266 |
| B | GLN267 |
| B | PRO268 |
| B | ASN286 |
| B | LYS287 |
| B | GLU288 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS224 | |
| B | CYS224 | |
| Chain | Residue | Details |
| A | SER122 | |
| B | GLU323 | |
| A | PHE132 | |
| A | TYR204 | |
| A | MET299 | |
| A | GLU323 | |
| B | SER122 | |
| B | PHE132 | |
| B | TYR204 | |
| B | MET299 | |
| Chain | Residue | Details |
| A | ILE232 | |
| A | GLU237 | |
| A | LEU258 | |
| A | GLY261 | |
| B | ILE232 | |
| B | GLU237 | |
| B | LEU258 | |
| B | GLY261 | |
| Chain | Residue | Details |
| A | ASP39 | |
| B | ASP39 | |
| Chain | Residue | Details |
| A | ASP60 | |
| A | LEU62 | |
| A | LEU64 | |
| B | ASP60 | |
| B | LEU62 | |
| B | LEU64 | |
| Chain | Residue | Details |
| A | SER90 | |
| A | GLU137 | |
| A | PHE244 | |
| B | SER90 | |
| B | GLU137 | |
| B | PHE244 | |
