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6NPL

Cryo-EM structure of NKCC1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Solute carrier family 12 (sodium/potassium/chloride transporter), member 2polymer914100643.42UniProt (A0A0G2KGS0)
Pfam (PF00324)
Pfam (PF03522)
UniProt (by SIFTS) (A0A0G2KTI4)
Danio rerio (Zebrafish)
2C, I
(A, B)
POTASSIUM IONnon-polymer39.12Chemie (K)
3D, E, J, K
(A, B)
CHLORIDE IONnon-polymer35.54Chemie (CL)
4F, G, H, L, M...
(A, B)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.17Chemie (POV)
Sequence modifications
A, B: 206 - 1136 (UniProt: A0A0G2KGS0)
PDBExternal DatabaseDetails
Ile 819Thr 819conflict
-Ala 919deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight201286.9
Non-Polymers*Number of molecules13
Total formula weight5540.5
All*Total formula weight206827.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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