6NPL
Cryo-EM structure of NKCC1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | polymer | 914 | 100643.4 | 2 | UniProt (A0A0G2KGS0) Pfam (PF00324) Pfam (PF03522) UniProt (by SIFTS) (A0A0G2KTI4) In PDB | Danio rerio (Zebrafish) | |
| 2 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | A, B | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 7 | Chemie (POV) |
Sequence modifications
A, B: 206 - 1136 (UniProt: A0A0G2KGS0)
| PDB | External Database | Details |
|---|---|---|
| Ile 819 | Thr 819 | conflict |
| - | Ala 919 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 201286.9 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 5540.5 | |
| All* | Total formula weight | 206827.4 |
