6NN7
The structure of human liver pyruvate kinase, hLPYK-GGG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, E, D...) | Pyruvate kinase PKLR | polymer | 542 | 58437.0 | 8 | UniProt (P30613) Pfam (PF00224) Pfam (PF02887) | Homo sapiens (Human) | Pyruvate kinase 1,Pyruvate kinase isozymes L/R,R-type/L-type pyruvate kinase,Red cell/liver pyruvate kinase |
| 2 | AA, FA, HA, I, J... (E, D, F, A, G...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 17 | Chemie (EDO) | |||
| 3 | BA, CA, DA, GA, IA... (E, D, F, A, G...) | GLYCEROL | non-polymer | 92.1 | 14 | Chemie (GOL) | |||
| 4 | EA, Q (D, C) | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
| 5 | PA, QA, RA, SA, TA... (A, B, C, E, D...) | water | water | 18.0 | 382 | Chemie (HOH) |
Sequence modifications
A, B, C, E, D, F, G, H: 3 - 543 (UniProt: P30613)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Glu 2 | - | expression tag |
| - | Pro 560 | deletion |
| Gly 531 | Ser 562 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 467496.2 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 2722.7 | |
| All* | Total formula weight | 470218.8 |
