6NMQ
Hypoxia-Inducible Factor (HIF) Prolyl Hydroxylase 2 (PHD2) in Complex with the Carboxamide Analog JNJ43058171
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Egl nine homolog 1 | polymer | 213 | 23929.2 | 1 | UniProt (Q9GZT9) Pfam (PF13640) | Homo sapiens (Human) | Hypoxia-inducible factor prolyl hydroxylase 2,HPH-2,Prolyl hydroxylase domain-containing protein 2,PHD2,SM-20 |
| 2 | B (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 3 | C (A) | N-(4-oxo-1,4-dihydrocinnoline-3-carbonyl)glycine | non-polymer | 247.2 | 1 | Chemie (KU1) | |||
| 4 | D (A) | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23929.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 303.1 | |
| All* | Total formula weight | 24232.3 |
