6NL7
Crystal structure of B1 immunoglobulin-binding domain of Streptococcal Protein G (T16F, T18A, V21H, T25H, K28Y, V29I, K31R, Q32A, Y33L, N35K, D36A, N37Q)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Immunoglobulin G-binding protein G | polymer | 56 | 6247.9 | 4 | UniProt (P19909) Pfam (PF01378) In PDB | Streptococcus | IgG-binding protein G |
2 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | A, B, C, D | ACETATE ION | non-polymer | 59.0 | 8 | Chemie (ACT) | |||
4 | A, B, C | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
6 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
7 | B | DIPHOSPHATE | non-polymer | 173.9 | 1 | Chemie (DPO) | |||
8 | water | water | 18.0 | 335 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 56 (UniProt: P19909)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Phe 16 | Thr 317 | engineered mutation |
Ala 18 | Thr 319 | engineered mutation |
His 21 | Val 322 | engineered mutation |
His 25 | Thr 326 | engineered mutation |
Tyr 28 | Lys 329 | engineered mutation |
Ile 29 | Val 330 | engineered mutation |
Arg 31 | Lys 332 | engineered mutation |
Ala 32 | Gln 333 | engineered mutation |
Leu 33 | Tyr 334 | engineered mutation |
Lys 35 | Asn 336 | engineered mutation |
Ala 36 | Asp 337 | engineered mutation |
Gln 37 | Asn 338 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 24991.8 | |
Non-Polymers* | Number of molecules | 20 |
Total formula weight | 1225.3 | |
All* | Total formula weight | 26217.1 |