6NK0

EphA2 LBD in complex with bA-WLA-Yam peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ephrin type-A receptor 2	polymer	187	21339.1	2	UniProt (P29317) Pfam (PF01404)	Homo sapiens (human)	Epithelial cell kinase,Tyrosine-protein kinase receptor ECK
2	C, D (C, D)	bA-WLA-Yam	polymer	12	1279.4	2		synthetic construct
3	E, H, K (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	F (A)	6-AMINOHEXANOIC ACID	non-polymer		131.2	1	Chemie (ACA)
5	G, J (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	I (B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
7	L, M, N, O (A, B, C, D)	water	water		18.0	395	Chemie (HOH)

Sequence modifications

A, B: 28 - 200 (UniProt: P29317)

PDB	External Database	Details
Met 21	-	expression tag
Ala 22	-	expression tag
Ser 23	-	expression tag
Gln 24	-	expression tag
Gly 25	-	expression tag
Pro 26	-	expression tag
Gly 27	-	expression tag
Ala 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	45237.1
Non-Polymers*	Number of molecules	7
	Total formula weight	637.7
All*	Total formula weight	45874.8

*Water molecules are not included.