6NE3

Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h bound at SHL-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3.2	polymer	136	15435.1	2	UniProt (P84233) Pfam (PF00125)	Xenopus laevis (African clawed frog)	Histone H3
2	B, F (B, F)	Histone H4	polymer	103	11394.4	2	UniProt (P62799) Pfam (PF15511)	Xenopus laevis (African clawed frog)
3	C, G (C, G)	Histone H2A type 1	polymer	130	14093.4	2	UniProt (P06897) Pfam (PF00125) Pfam (PF16211)	Xenopus laevis (African clawed frog)
4	D (D)	Histone H2B	polymer	99	11180.0	1	UniProt (A0A1L8FQ56) Pfam (PF00125) UniProt (by SIFTS) (P02281)	Xenopus laevis (African clawed frog)
5	H (H)	Histone H2B	polymer	93	10348.9	1	UniProt (A0A1L8FQ56) Pfam (PF00125) UniProt (by SIFTS) (P02281)	Xenopus laevis (African clawed frog)
6	I (J)	DNA (156-MER)	polymer	156	47936.5	1		Xenopus laevis (African clawed frog)
7	J (I)	DNA (156-MER)	polymer	156	48372.8	1		Xenopus laevis (African clawed frog)
8	K (W)	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	polymer	467	54653.3	1	UniProt (O60264) Pfam (PF00176) Pfam (PF00271)	Homo sapiens (Human)	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5,Sucrose nonfermenting protein 2 homolog,hSNF2H
9	L (W)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)

Sequence modifications

A, E: 0 - 135 (UniProt: P84233)

PDB	External Database	Details
Ala 102	Gly 103	engineered mutation

C, G: 0 - 129 (UniProt: P06897)

PDB	External Database	Details
Arg 99	Gly 100	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	254337.5
Non-Polymers*	Number of molecules	1
	Total formula weight	427.2
All*	Total formula weight	254764.7

*Water molecules are not included.