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6N5X

Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sorting nexin-5,Cation-independent mannose-6-phosphate receptorpolymer18221024.41UniProt (Q9Y5X3)
UniProt (P11717)
Pfam (PF00787)
Homo sapiens (Human)M6PR,300 kDa mannose 6-phosphate receptor,MPR 300,Insulin-like growth factor 2 receptor,Insulin-like growth factor II receptor,IGF-II receptor,M6P/IGF2 receptor,M6P/IGF2R
2B
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
3C
(A)
O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)non-polymer597.81Chemie (JEF)
4D
(A)
waterwater18.081Chemie (HOH)
Sequence modifications
A: 22 - 170 (UniProt: Q9Y5X3)
PDBExternal DatabaseDetails
Gly 20-expression tag
Ser 21-expression tag
A: 171 - 201 (UniProt: P11717)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight21024.4
Non-Polymers*Number of molecules2
Total formula weight689.9
All*Total formula weight21714.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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