6N55
Crystal structure of human uridine-cytidine kinase 2 complexed with 2'-azidouridine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Uridine-cytidine kinase 2 | polymer | 255 | 28520.3 | 8 | UniProt (Q9BZX2) Pfam (PF00485) | Homo sapiens (Human) | UCK 2,Cytidine monophosphokinase 2,Testis-specific protein TSA903,Uridine monophosphokinase 2 |
| 2 | EA, I, KA, N, R... (E, A, F, B, C...) | PHOSPHATE ION | non-polymer | 95.0 | 8 | Chemie (PO4) | |||
| 3 | AA, BA, CA, FA, GA... (D, E, A, F, B...) | GLYCEROL | non-polymer | 92.1 | 27 | Chemie (GOL) | |||
| 4 | DA, JA, QA (D, E, F) | 2'-azido-2'-deoxyuridine | non-polymer | 269.2 | 3 | Chemie (UZ0) | |||
| 5 | AB, BB, UA, VA, WA... (G, H, A, B, C...) | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 250 (UniProt: Q9BZX2)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 228162.3 | |
| Non-Polymers* | Number of molecules | 38 |
| Total formula weight | 4053.9 | |
| All* | Total formula weight | 232216.2 |
