6N54
Crystal structure of human uridine-cytidine kinase 2 complexed with 2'-azidocytidine monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Uridine-cytidine kinase 2 | polymer | 255 | 28520.3 | 2 | UniProt (Q9BZX2) Pfam (PF00485) | Homo sapiens (Human) | UCK 2,Cytidine monophosphokinase 2,Testis-specific protein TSA903,Uridine monophosphokinase 2 |
| 2 | C, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, H, I, J, K... (A, B) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 4 | E, N (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | F, O (A, B) | 2'-azido-2'-deoxycytidine 5'-(dihydrogen phosphate) | non-polymer | 348.2 | 2 | Chemie (KEA) | |||
| 6 | P, Q (A, B) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 250 (UniProt: Q9BZX2)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57040.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1579.6 | |
| All* | Total formula weight | 58620.2 |
