6N52

Metabotropic Glutamate Receptor 5 Apo Form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Metabotropic glutamate receptor 5	polymer	871	97677.9	2	UniProt (P41594) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003)	Homo sapiens (Human)	mGluR5
2	C, D, E, F (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)

Sequence modifications

A, B: 20 - 839 (UniProt: P41594)

PDB	External Database	Details
Met -5	-	initiating methionine
Lys -4	-	expression tag
Thr -3	-	expression tag
Ile -2	-	expression tag
Ile -1	-	expression tag
Ala 0	-	expression tag
Leu 1	-	expression tag
Ser 2	-	expression tag
Tyr 3	-	expression tag
Ile 4	-	expression tag
Phe 5	-	expression tag
Cys 6	-	expression tag
Leu 7	-	expression tag
Val 8	-	expression tag
Phe 9	-	expression tag
Ala 10	-	expression tag
Asp 11	-	expression tag
Tyr 12	-	expression tag
Lys 13	-	expression tag
Asp 14	-	expression tag
Asp 15	-	expression tag
Asp 16	-	expression tag
Asp 17	-	expression tag
Ala 18	-	expression tag
Ala 19	-	expression tag
Ser 840	-	expression tag
Thr 841	-	expression tag
Val 842	-	expression tag
Val 843	-	expression tag
Arg 844	-	expression tag
Met 845	-	expression tag
His 846	-	expression tag
Val 847	-	expression tag
Gly 848	-	expression tag
Asp 849	-	expression tag
Gly 850	-	expression tag
Lys 851	-	expression tag
Ser 852	-	expression tag
Ser 853	-	expression tag
Ser 854	-	expression tag
Ala 855	-	expression tag
Ala 856	-	expression tag
Ser 857	-	expression tag
Arg 858	-	expression tag
Ser 859	-	expression tag
Ser 860	-	expression tag
Ser 861	-	expression tag
Leu 862	-	expression tag
Val 863	-	expression tag
Asn 864	-	expression tag
Leu 865	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	195355.9
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	196240.7

*Water molecules are not included.