6N4I
Structural basis of Nav1.7 inhibition by a gating-modifier spider toxin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Nav1.7 VSD2-NavAb channel chimera protein | polymer | 288 | 33453.5 | 4 | Homo sapiens | ||
| 2 | E, F, G, H (E, F, G, H) | Beta/omega-theraphotoxin-Tp2a | polymer | 30 | 3839.7 | 4 | UniProt (P83476) | Thrixopelma pruriens (Peruvian green velvet tarantula) | Beta/omega-TRTX-Tp2a,ProTx-II,PT-II,Protoxin-2,ProTx2 |
| 3 | I, J, K, L, M... (A, B, C, D, E...) | [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | non-polymer | 718.0 | 16 | Chemie (6OU) PubChem (3246975) PubChem (5282290) PubChem (5283496) PubChem (5785226) PubChem (23727968) PubChem (123931) PubChem (90470676) PubChem (92863393) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 149172.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 11487.9 | |
| All* | Total formula weight | 160660.7 |
