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6N3X

Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound 5'-O-[1-Benzyl]Carbamoyl Guanosine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Histidine triad nucleotide-binding protein 1polymer12914096.22UniProt (P49773)
Pfam (PF01230)
Homo sapiens (Human)Adenosine 5'-monophosphoramidase,Protein kinase C inhibitor 1,Protein kinase C-interacting protein 1,PKCI-1
2C
(A)
5'-O-(benzylcarbamoyl)guanosinenon-polymer416.41Chemie (KBD)
3D, E
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
4F
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5G, H
(A, B)
waterwater18.0282Chemie (HOH)
Sequence modifications
A, B: 1 - 126 (UniProt: P49773)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28192.4
Non-Polymers*Number of molecules4
Total formula weight576.0
All*Total formula weight28768.4
*Water molecules are not included.

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PDB entries from 2026-01-21

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