6N0Z
Crystal structure of Anaerolinea thermophila mevalonate 5-phosphate decarboxylase N20K H194M mutant complexed with (R)-MVAPP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Diphosphomevalonate decarboxylase | polymer | 330 | 35752.8 | 6 | UniProt (E8N6F3) Pfam (PF22700) Pfam (PF18376) In PDB | Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1) | |
| 2 | A, B, C, D, E... | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID | non-polymer | 308.1 | 6 | Chemie (DP6) | |||
| 3 | water | water | 18.0 | 1754 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 326 (UniProt: E8N6F3)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Lys 20 | Asn 20 | engineered mutation |
| Met 194 | His 194 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 214516.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1848.7 | |
| All* | Total formula weight | 216365.3 |
