6MXY

Structure of 53BP1 tandem Tudor domains in complex with small molecule UNC3351

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	TP53-binding protein 1	polymer	123	13944.8	2	UniProt (Q12888) Pfam (PF09038)	Homo sapiens (Human)	p53BP1
2	C, D, F, G, H (A, B)	PHOSPHATE ION	non-polymer		95.0	5	Chemie (PO4)
3	E (B)	N-[3-(tert-butylamino)propyl]-3-(trifluoromethyl)benzamide	non-polymer		302.3	1	Chemie (K6M)
4	I, J (A, B)	water	water		18.0	348	Chemie (HOH)

Sequence modifications

A, B: 1484 - 1603 (UniProt: Q12888)

PDB	External Database	Details
Gly 1481	-	expression tag
His 1482	-	expression tag
Met 1483	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27889.6
Non-Polymers*	Number of molecules	6
	Total formula weight	777.2
All*	Total formula weight	28666.8

*Water molecules are not included.