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6MXG

Crystal structure of Trypanosoma brucei hypoxanthine-guanine phosphoribosyltranferase in complex with XMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Hypoxanthine-guanine phosphoribosyltransferasepolymer21624221.82UniProt (Q07010)
Pfam (PF00156)
Trypanosoma brucei bruceiHGPRTase
2C, G
(A, B)
XANTHOSINE-5'-MONOPHOSPHATEnon-polymer365.22Chemie (XMP)
3D, E, H, I
(A, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
4F, J
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
5K, L
(A, B)
waterwater18.059Chemie (HOH)
Sequence modifications
A, B: 1 - 210 (UniProt: Q07010)
PDBExternal DatabaseDetails
His -5-expression tag
His -4-expression tag
His -3-expression tag
His -2-expression tag
His -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight48443.6
Non-Polymers*Number of molecules8
Total formula weight1019.8
All*Total formula weight49463.3
*Water molecules are not included.

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PDB entries from 2025-07-16

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