6MX0
Crystal structure of human STING apoprotein (G230A, H232R, R293Q)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Stimulator of interferon genes protein | polymer | 188 | 21528.2 | 2 | UniProt (Q86WV6) Pfam (PF15009) | Homo sapiens (Human) | hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173 |
| 2 | C (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A, B: 155 - 341 (UniProt: Q86WV6)
| PDB | External Database | Details |
|---|---|---|
| Ser 154 | - | expression tag |
| Ala 230 | Gly 230 | engineered mutation |
| Arg 232 | His 232 | engineered mutation |
| Gln 293 | Arg 293 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43056.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 43096.4 |
