6MWE
CRYSTAL STRUCTURE OF TIE2 IN COMPLEX WITH DECIPERA COMPOUND DP1919
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Angiopoietin-1 receptor | polymer | 317 | 36253.3 | 2 | UniProt (Q02763) Pfam (PF07714) In PDB | Homo sapiens (Human) | Endothelial tyrosine kinase,Tunica interna endothelial cell kinase,Tyrosine kinase with Ig and EGF homology domains-2,Tyrosine-protein kinase receptor TEK,Tyrosine-protein kinase receptor TIE-2,hTIE2,p140 TEK |
2 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
3 | A, B | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide | non-polymer | 553.6 | 2 | Chemie (919) | |||
4 | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 72506.7 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1491.4 | |
All* | Total formula weight | 73998.1 |