Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 1201 |
| Chain | Residue |
| A | ARG999 |
| A | CYS1044 |
| A | ALA1045 |
| A | HOH1302 |
| B | HIS881 |
| B | TYR954 |
| B | LYS958 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 1202 |
| Chain | Residue |
| A | GLN939 |
| A | HIS943 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue 919 A 1203 |
| Chain | Residue |
| A | ILE830 |
| A | ALA853 |
| A | LYS855 |
| A | GLU872 |
| A | VAL875 |
| A | LEU876 |
| A | ILE885 |
| A | ILE886 |
| A | GLU903 |
| A | ALA905 |
| A | GLY908 |
| A | ALA981 |
| A | ASP982 |
| A | PHE983 |
| A | GLY984 |
| A | ARG987 |
| A | GLN989 |
| A | HOH1376 |
| A | HOH1401 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 1201 |
| Chain | Residue |
| A | TYR1015 |
| A | HOH1325 |
| B | ARG950 |
| B | ASN1093 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 1202 |
| Chain | Residue |
| B | GLN939 |
| B | HIS943 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | binding site for residue 919 B 1203 |
| Chain | Residue |
| B | ILE830 |
| B | ALA853 |
| B | LYS855 |
| B | GLU872 |
| B | LEU876 |
| B | ILE885 |
| B | ILE886 |
| B | ILE902 |
| B | GLU903 |
| B | TYR904 |
| B | ALA905 |
| B | PHE960 |
| B | ILE980 |
| B | ALA981 |
| B | ASP982 |
| B | PHE983 |
| B | GLY984 |
| B | ARG987 |
| B | GLN989 |
| B | HOH1383 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 26 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGEGNFGQVLkArikkdglrmd........AAIK |
| Chain | Residue | Details |
| A | ILE830-LYS855 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FIHrDLAARNILV |
| Chain | Residue | Details |
| A | PHE960-VAL972 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"11080633","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"11513602","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"14665640","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27270174","evidenceCode":"ECO:0000269"}]} |
