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6MQT

HRAS G12S in complex with GDP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
GTPase HRaspolymer16718976.38UniProt (P01112)
Pfam (PF00071)
Homo sapiens (Human)H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras
2I, K, M, O, Q...
(A, B, C, D, E...)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.28Chemie (GDP)
3J, L, N, P, R...
(A, B, C, D, E...)
MAGNESIUM IONnon-polymer24.38Chemie (MG)
4AA, BA, CA, DA, EA...
(C, D, E, F, G...)
waterwater18.01027Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 166 (UniProt: P01112)
PDBExternal DatabaseDetails
Ala 0-expression tag
Ser 12Gly 12engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight151810.4
Non-Polymers*Number of molecules16
Total formula weight3740.0
All*Total formula weight155550.4
*Water molecules are not included.

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PDB entries from 2026-01-28

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