6MOJ
Dimeric DARPin A_angle_R5 complex with EpoR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dimeric DARPin ACR5 (A_angle_R5) | polymer | 231 | 24261.7 | 1 | synthetic construct | ||
| 2 | B (B) | Erythropoietin receptor | polymer | 229 | 25129.4 | 1 | UniProt (P19235) Pfam (PF09067) Pfam (PF00041) | Homo sapiens (Human) | EPO-R |
| 3 | C, D, E (A, B) | D(-)-TARTARIC ACID | non-polymer | 150.1 | 3 | Chemie (TAR) | |||
| 4 | F, G, H (B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
B: 8 - 225 (UniProt: P19235)
| PDB | External Database | Details |
|---|---|---|
| Phe 3 | - | expression tag |
| Ala 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Gln 52 | Asn 76 | conflict |
| Gln 164 | Asn 188 | conflict |
| Lys 226 | - | expression tag |
| Glu 227 | - | expression tag |
| Lys 228 | - | expression tag |
| Ala 229 | - | expression tag |
| Ala 230 | - | expression tag |
| Ala 231 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49391.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 726.5 | |
| All* | Total formula weight | 50117.6 |
