6MOJ
Dimeric DARPin A_angle_R5 complex with EpoR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dimeric DARPin ACR5 (A_angle_R5) | polymer | 231 | 24261.7 | 1 | synthetic construct | ||
2 | B | Erythropoietin receptor | polymer | 229 | 25129.4 | 1 | UniProt (P19235) Pfam (PF09067) Pfam (PF00041) In PDB | Homo sapiens (Human) | EPO-R |
3 | A, B | D(-)-TARTARIC ACID | non-polymer | 150.1 | 3 | Chemie (TAR) | |||
4 | B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
B: 8 - 225 (UniProt: P19235)
PDB | External Database | Details |
---|---|---|
Phe 3 | - | expression tag |
Ala 4 | - | expression tag |
Gly 5 | - | expression tag |
Ser 6 | - | expression tag |
Ala 7 | - | expression tag |
Gln 52 | Asn 76 | conflict |
Gln 164 | Asn 188 | conflict |
Lys 226 | - | expression tag |
Glu 227 | - | expression tag |
Lys 228 | - | expression tag |
Ala 229 | - | expression tag |
Ala 230 | - | expression tag |
Ala 231 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 49391.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 726.5 | |
All* | Total formula weight | 50117.6 |