6MOH
Dimeric DARPin C_R3 complex with EpoR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dimeric DARPin E2C (C_R3) | polymer | 165 | 17565.1 | 2 | synthetic construct | ||
| 2 | C, D (C, D) | Erythropoietin receptor | polymer | 229 | 25129.4 | 2 | UniProt (P19235) Pfam (PF09067) Pfam (PF00041) | Homo sapiens (Human) | EPO-R |
| 3 | E, F, G, I, J... (A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 7 | Chemie (PO4) | |||
| 4 | H (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | M, N, O (A, B, C) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
C, D: 8 - 225 (UniProt: P19235)
| PDB | External Database | Details |
|---|---|---|
| Phe 3 | - | expression tag |
| Ala 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Gln 52 | Asn 76 | conflict |
| Gln 164 | Asn 188 | conflict |
| Lys 226 | - | expression tag |
| Glu 227 | - | expression tag |
| Lys 228 | - | expression tag |
| Ala 229 | - | expression tag |
| Ala 230 | - | expression tag |
| Ala 231 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 85389.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 687.8 | |
| All* | Total formula weight | 86076.9 |
