6MO5
Co-Crystal structure of P. aeruginosa LpxC-50228 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 304 | 33742.2 | 1 | UniProt (P47205) Pfam (PF03331) | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | B (A) | N-[(2S)-1-(hydroxyamino)-3-methyl-3-{[(oxetan-3-yl)methyl]sulfonyl}-1-oxobutan-2-yl]-4-(6-hydroxyhexa-1,3-diyn-1-yl)benzamide | non-polymer | 462.5 | 1 | Chemie (JWP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A: 2 - 299 (UniProt: P47205)
| PDB | External Database | Details |
|---|---|---|
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Thr 1 | - | expression tag |
| Val 129 | Ile 129 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33742.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 486.8 | |
| All* | Total formula weight | 34229.0 |
