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6MO5

Co-Crystal structure of P. aeruginosa LpxC-50228 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0005737cellular_componentcytoplasm
A0006629biological_processlipid metabolic process
A0009245biological_processlipid A biosynthetic process
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0046872molecular_functionmetal ion binding
A0103117molecular_functionUDP-3-O-acyl-N-acetylglucosamine deacetylase activity
Functional Information from PDB Data
site_idAC1
Number of Residues20
Detailsbinding site for residue JWP A 301
ChainResidue
AHIS19
AILE197
AALA206
AGLY209
ASER210
AHIS237
AASP241
AHIS264
AMG302
AHOH408
AHOH452
AMET62
AHOH476
AGLU77
AHIS78
ATHR190
APHE191
AGLY192
APHE193
AASP196

site_idAC2
Number of Residues4
Detailsbinding site for residue MG A 302
ChainResidue
AHIS78
AHIS237
AASP241
AJWP301

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsActive site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00388","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues3
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00388","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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