6MNX
Structural basis of impaired hydrolysis in KRAS Q61H mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | GTPase KRas | polymer | 169 | 19281.8 | 6 | UniProt (P01116) Pfam (PF00071) In PDB | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
2 | A, B, C, D, E... | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 6 | Chemie (GTP) | |||
3 | A, B, C, D, E... | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
4 | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 169 (UniProt: P01116)
PDB | External Database | Details |
---|---|---|
His 61 | Gln 61 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 115690.7 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 3284.9 | |
All* | Total formula weight | 118975.6 |