6MKE

Crystal Structure of Peptidylprolyl Isomerase from Naegleria fowleri with bound FK506

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Peptidylprolyl isomerase	polymer	127	14206.2	4	UniProt (A0A2H4A315) Pfam (PF00254) In PDB	Naegleria fowleri (Brain eating amoeba)
2	A, B, C, D	8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	non-polymer		804.0	4	Chemie (FK5)
3		water	water		18.0	384	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 119 (UniProt: A0A2H4A315)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	56824.7
Non-Polymers*	Number of molecules	4
	Total formula weight	3216.1
All*	Total formula weight	60040.7

*Water molecules are not included.