6MJK

Crystal Structure of dUTP pyrophosphatase protein, from Naegleria fowleri in complex with deoxyuridine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	dUTP pyrophosphatase	polymer	155	16843.1	1	UniProt (A0A1Z0YU86) Pfam (PF00692) In PDB	Naegleria fowleri (Brain eating amoeba)	NafoA.01242.a.B1
2	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	A	2'-DEOXYURIDINE	non-polymer		228.2	1	Chemie (DUR)
4	A	PYROPHOSPHATE	non-polymer		178.0	1	Chemie (PPV)
5		water	water		18.0	166	Chemie (HOH)

Sequence modifications

A: 1 - 147 (UniProt: A0A1Z0YU86)

PDB	External Database	Details
Met -7	-	expression tag
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	16843.1
Non-Polymers*	Number of molecules	4
	Total formula weight	454.8
All*	Total formula weight	17297.9

*Water molecules are not included.