6MJK
Crystal Structure of dUTP pyrophosphatase protein, from Naegleria fowleri in complex with deoxyuridine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004170 | molecular_function | dUTP diphosphatase activity |
| A | 0006226 | biological_process | dUMP biosynthetic process |
| A | 0009117 | biological_process | nucleotide metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046081 | biological_process | dUTP catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 201 |
| Chain | Residue |
| A | SER22 |
| A | PPV204 |
| A | HOH318 |
| A | HOH341 |
| A | HOH356 |
| A | HOH388 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 202 |
| Chain | Residue |
| A | HOH309 |
| A | HOH309 |
| A | HOH309 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue DUR A 203 |
| Chain | Residue |
| A | SER67 |
| A | ALA79 |
| A | GLY80 |
| A | VAL81 |
| A | ASP83 |
| A | TYR86 |
| A | GLY91 |
| A | GLY138 |
| A | PHE139 |
| A | PPV204 |
| A | HOH314 |
| A | HOH341 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue PPV A 204 |
| Chain | Residue |
| A | ARG66 |
| A | SER67 |
| A | GLY68 |
| A | ARG134 |
| A | PHE139 |
| A | GLY140 |
| A | SER141 |
| A | THR142 |
| A | MG201 |
| A | DUR203 |
| A | HOH356 |
| A | HOH388 |
| A | HOH399 |
