6MJ5

Crystal structure of Tdp1 catalytic domain in complex with compound XZ519

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tyrosyl-DNA phosphodiesterase 1	polymer	460	52039.3	2	UniProt (Q9NUW8) Pfam (PF06087) In PDB	Homo sapiens (Human)	Tyr-DNA phosphodiesterase 1
2	A, B	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
3	A, B	4-hydroxy-8-nitroquinoline-3-carboxylic acid	non-polymer		234.2	2	Chemie (JTA)
4		water	water		18.0	580	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	104078.5
Non-Polymers*	Number of molecules	7
	Total formula weight	778.7
All*	Total formula weight	104857.2

*Water molecules are not included.