6MIB
Crystal structure of the ILK ATP-binding deficient mutant (L207W)/alpha-parvin core complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin-linked protein kinase | polymer | 271 | 31045.1 | 1 | UniProt (Q13418) Pfam (PF07714) | Homo sapiens (Human) | 59 kDa serine/threonine-protein kinase,ILK-1,ILK-2,p59ILK |
| 2 | B (B) | Alpha-parvin | polymer | 129 | 14843.1 | 1 | UniProt (Q9NVD7) Pfam (PF00307) | Homo sapiens (Human) | Actopaxin,CH-ILKBP,Calponin-like integrin-linked kinase-binding protein,Matrix-remodeling-associated protein 2 |
| 3 | C, D (A, B) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A: 182 - 452 (UniProt: Q13418)
B: 248 - 372 (UniProt: Q9NVD7)
| PDB | External Database | Details |
|---|---|---|
| Met 182 | Leu 182 | conflict |
| Trp 207 | Leu 207 | engineered mutation |
| Ser 346 | Cys 346 | conflict |
| Ser 422 | Cys 422 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 244 | - | expression tag |
| Ser 245 | - | expression tag |
| His 246 | - | expression tag |
| Met 247 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45888.1 | |
| All* | Total formula weight | 45888.1 |
