6MI2
Structure of the human 4-1BB / Utomilumab Fab complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Utomilumab Fab heavy chain | polymer | 230 | 24755.7 | 2 | Homo sapiens (Human) | ||
2 | B, E | Utomilumab Fab lambda chain | polymer | 214 | 22699.0 | 2 | Homo sapiens (Human) | ||
3 | F, C | Tumor necrosis factor receptor superfamily member 9 | polymer | 145 | 15727.7 | 2 | UniProt (Q07011) Pfam (PF00020) In PDB | Homo sapiens (Human) | 4-1BB ligand receptor,CDw137,T-cell antigen 4-1BB homolog,T-cell antigen ILA |
4 | G | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
5 | F, C, A, B, D... | SULFATE ION | non-polymer | 96.1 | 20 | Chemie (SO4) | |||
6 | C, A, B, E | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
7 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
8 | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
F, C: 25 - 162 (UniProt: Q07011)
PDB | External Database | Details |
---|---|---|
Glu 163 | - | expression tag |
Asn 164 | - | expression tag |
Leu 165 | - | expression tag |
Tyr 166 | - | expression tag |
Phe 167 | - | expression tag |
Gln 168 | - | expression tag |
Gly 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 126364.8 | |
Branched | Number of molecules | 1 |
Total formula weight | 367.3 | |
Non-Polymers* | Number of molecules | 30 |
Total formula weight | 2971.3 | |
All* | Total formula weight | 129703.5 |