6MI2
Structure of the human 4-1BB / Utomilumab Fab complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | Utomilumab Fab heavy chain | polymer | 230 | 24755.7 | 2 | Homo sapiens (Human) | ||
| 2 | B, D (B, E) | Utomilumab Fab lambda chain | polymer | 214 | 22699.0 | 2 | Homo sapiens (Human) | ||
| 3 | E, F (F, C) | Tumor necrosis factor receptor superfamily member 9 | polymer | 145 | 15727.7 | 2 | UniProt (Q07011) Pfam (PF00020) | Homo sapiens (Human) | 4-1BB ligand receptor,CDw137,T-cell antigen 4-1BB homolog,T-cell antigen ILA |
| 4 | G (G) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 5 | AA, CA, DA, EA, FA... (F, C, A, B, D...) | SULFATE ION | non-polymer | 96.1 | 20 | Chemie (SO4) | |||
| 6 | IA, JA, K, KA, Q... (C, A, B, E) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 7 | BA (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 8 | LA, MA, NA, OA, PA... (A, B, D, E, F...) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
F, C: 25 - 162 (UniProt: Q07011)
| PDB | External Database | Details |
|---|---|---|
| Glu 163 | - | expression tag |
| Asn 164 | - | expression tag |
| Leu 165 | - | expression tag |
| Tyr 166 | - | expression tag |
| Phe 167 | - | expression tag |
| Gln 168 | - | expression tag |
| Gly 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 126364.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 367.3 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 2971.3 | |
| All* | Total formula weight | 129703.5 |
